Mycoplasma pneumoniae

Determination of the gene regulatory network of a genome-reduced bacterium highlights alternative regulation independent of transcription factors
Here, we determined the relative importance of different transcriptional mechanisms in the genome-reduced bacterium Mycoplasma …
Eva Yus, Verónica Lloréns-Rico, Sira Martínez, Carolina Gallo, Hinnerk Eilers, Cedric Bloetz, Joerg Stuelke, Maria Lluch-Senar, Luis Serrano
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Determination of the gene regulatory network of a genome-reduced bacterium highlights alternative regulation independent of transcription factors
Insights into the mechanisms of basal coordination of transcription using a genome-reduced bacterium
Coordination of transcription in bacteria occurs at supra-operonic scales, but the extent, specificity, and mechanisms of such …
Ivan Junier, E Besray Unal, Eva Yus, Verónica Lloréns-Rico, Luis Serrano
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Bacterial antisense RNAs are mainly the product of transcriptional noise
cis-Encoded antisense RNAs (asRNAs) are widespread along bacterial transcriptomes. However, the role of most of these RNAs remains …
Verónica Lloréns-Rico, Jaime Cano, Tjerko Kamminga, Rosario Gil, Amparo Latorre, Wei-Hua Chen, Peer Bork, John I Glass, Luis Serrano, Maria Lluch-Senar
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Comparative “-omics” in Mycoplasma pneumoniae clinical isolates reveals key virulence factors
The human respiratory tract pathogen M. pneumoniae is one of the best characterized minimal bacterium. Until now, two main groups of …
Maria Lluch-Senar, Luca Cozzuto, Jaime Cano, Javier Delgado, Verónica Lloréns-Rico, Sabine Pereyre, Cécile Bebear, Luis Serrano
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Distinguishing between productive and abortive promoters using a random forest classifier in Mycoplasma pneumoniae
Distinguishing between promoter-like sequences in bacteria that belong to true or abortive promoters, or to those that do not initiate …
Verónica Lloréns-Rico, Maria Lluch-Senar, Luis Serrano
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Defining a minimal cell: essentiality of small ORF s and nc RNA s in a genome‐reduced bacterium
Identifying all essential genomic components is critical for the assembly of minimal artificial life. In the genome-reduced bacterium …
Maria Lluch‐Senar, Javier Delgado, Wei‐Hua Chen, Verónica Lloréns-Rico, Francis J O'Reilly, Judith AH Wodke, E Besray Unal, Eva Yus, Sira Martínez, Robert J Nichols, Tony Ferrar, Ana Vivancos, Arne Schmeisky, Jörg Stülke, Vera van Noort, Anne‐Claude Gavin, Peer Bork, Luis Serrano
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Assessing the hodgepodge of non-mapped reads in bacterial transcriptomes: real or artifactual RNA chimeras?
Background - RNA sequencing methods have already altered our view of the extent and complexity of bacterial and eukaryotic …
Verónica Lloréns-Rico, Luis Serrano, Maria Lluch-Senar
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Comprehensive Methylome Characterization of Mycoplasma genitalium and Mycoplasma pneumoniae at Single-Base Resolution
In the bacterial world, methylation is most commonly associated with restriction-modification systems that provide a defense mechanism …
Maria Lluch-Senar, Khai Luong, Verónica Lloréns-Rico, Javier Delgado, Gang Fang, Kristi Spittle, Tyson A Clark, Eric Schadt, Stephen W Turner, Jonas Korlach, Luis Serrano
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